Caltech Startups

Active Spectrum

Physical science

Advanced spectroscopy techniques

Caltech Founders: White
Year Founded: 2007
Foster City, CA 94404
United States

Adaptive Computation

Software/internet

Combination hardware and software based facial recognition, image based search engine and intelligent video under real world environment

Caltech Founders: Duong (JPL)
CEO/President: Tuan Duong
Year Founded: 2011
Glendora, CA 91741
United States

Advanced Telesensors

Life science

Remote sensing of cardiac-related waveforms

Caltech Founders: McGrath (JPL)
CEO/President: Malcolm Cloyd
Year Founded: 2009
Pasadena, CA 91107
United States

Alerion

Life science

MRI Contrast Agents

Caltech Founders: Meade
Year Founded: 1997
United States

Aliva Biopharmaceuticals

Life science

Bacterial Essential Genes & Methods for Transgenic Mice

Caltech Founders: Shizuya
CEO/President: Larry L. Green
Year Founded: 1999
Company Status: Acquired by Ablexis
Pasadena, CA 91105
United States

Allozyne

Life science

Engineered proteins containing non-natural amino acids for therapeutic, diagnostic or research applications

Caltech Founders: Tirrell, Goddard
CEO/President: Meenu Chhabra
Year Founded: 2005
Seattle, WA 98102
United States

Alta Devices

Physical science

Photovoltaic solar cells made of thin film gallium arsenide

Caltech Founders: Atwater
Year Founded: 2008
Sunnyvale, CA 94085
United States

Analytical Pixels

Physical science
Caltech Founders: Roukes
CEO/President: Phillipe Anndreucci
Year Founded: 2012
n/a Grenoble
France

Anchovi Labs

Software/internet

Image analysis through machine vision and crowd-sourced annotation

Caltech Founders: Perona
CEO/President: Boris Babenko
Year Founded: 2012
Exit Year: 2012
Company Status: Acquired by Dropbox
San Diego, CA 92126
United States

Aonex

Physical science

Semiconductor wafer layer transfer technology

Caltech Founders: Atwater
Year Founded: 2004
Exit Year: 2008
Company Status: acquired by Amberwave
Pasadena, CA 91107
United States

AquaNano

Chemistry

Dendrimer-like molecules for water filtration

Caltech Founders: Diallo
Year Founded: 2007
Monrovia, CA
United States

Arges Imaging

Life science

Dental Profilometry (scanning for crown molds)

Caltech Founders: Gharib
Year Founded: 2008
Exit Year: 2011
Company Status: acquired by Sirona
Pasadena, CA 91106
United States

Arithmos

Physical science

LCD Addressing Products

Caltech Founders: Mead, Yariv
Year Founded: 1995
Company Status: acquired by ST Microelectronics
United States

Arizona Microsystems

Physical science

Optical & Polymer Technologies

Caltech Founders: Marder, Perry
Year Founded: 2001
Exit Year: 2008
Company Status: acquired
Tucson, AZ 85747
United States

Arroyo Sciences

Software/internet

U-Hunter and MUDDS Software

Caltech Founders: Gulati (JPL)
CEO/President: Carl Kukkonen
Year Founded: 2003
Pasadena, CA 91107
United States

Aurora Biosciences

Life science

Screening for the identification of drug or agrochemical development candidates

Caltech Founders: Simon
Year Founded: 1995
Exit Year: 1997
Company Status: IPO
San Diego, CA 92121
United States

Avidity Nanomedicines

Life science

Delivery of siRNA to tumors

Caltech Founders: Davis
Year Founded: 2013
United States

Axiom Microdevices

Physical science

Wireless Semiconductors

Caltech Founders: Hajimiri
Year Founded: 2002
Exit Year: 2009
Company Status: acquired by Skyworks
Irvine, CA 92617
United States

Bionic Harvest

Physical science

Electret generator

Caltech Founders: Tai
CEO/President: Justin Boland
Year Founded: 2005
Pasadena, CA 91001
United States

Bionomix

Life science

Protein Structure Prediction Software

Caltech Founders: Goddard
Year Founded: 2000
Company Status: acquired by Eidogen-Sertanty
Pasadena, CA 91106
United States

BLS Diagnostics

Life science

Non-Invasive Method of Measuring Cerebral Spinal Fluid Pressure

Caltech Founders: Lambert (JPL)
Year Founded: 1998
Los Angeles, CA 90027
United States

Caelux

Physical science

Solar photovoltaic technology using silicon wires (flexible solar cells)

Caltech Founders: Atwater
CEO/President: John Iannelli
Year Founded: 2011
Pasadena, CA 91107
United States

Calando Pharmaceuticals

Life science

Improved inhibitor nucleic acids

Caltech Founders: Davis
CEO/President: Christopher Anzalone
Year Founded: 2005
Pasadena, CA 91101
United States

Calhoun Vision

Life science

Intraocular Lens Technology

Caltech Founders: Grubbs, Kornfield
CEO/President: Verne Sharma
Year Founded: 1997
Pasadena, CA 91107
United States

California Gamma Technologies

Physical science

Mask works for ASIC designs for chips used to detect high-frequency radiation

Caltech Founders: Harrison
CEO/President: Ryan McLean
Year Founded: 2009
Pasadena, CA 91106
United States

Calimmune

Life science

Lentiviral vectors for treatment of viral diseases including HIV

Caltech Founders: Baltimore
CEO/President: Louis Breton
Year Founded: 2006
Tucson, AZ 85711
United States

Callisto Intelligent Systems

Software/internet

Knowledge-based, massive data mining and computational intensive applications based on SHINE software

Caltech Founders: James (JPL)
CEO/President: AJ Abdallat
Year Founded: 2012
Thousand Oaks, CA 91360
United States

Cellicon Biotechnologies

Life science

Technologies for decoding the protein pathway for the cure of human diseases such as diabetes, arthritis, and cancer

Caltech Founders: Bailey (JPL)
CEO/President: Timothy Gardner
Year Founded: 2001
Boston, MA 02216
United States

Chromacode

Life science

Multiplex PCR technology

Caltech Founders: Scherer
Year Founded: 2013
United States

Cielo Engineering Software

Software/internet

Stand-alone, MATLAB hosted, general purpose finite element toolkit with high-performance computing for thermal and structural analysis, including optical results processing

Caltech Founders: Hoff (JPL)
Year Founded: 2011
Topanga, CA 90290
United States

Clearbridge Biophotonics

Life science

Wide field of view microscopy

Caltech Founders: Yang
CEO/President: Johnson Chen
Year Founded: 2010
n/a Singapore
Slovakia

Cleave Biosciences

Life science

Cancer therapeutics- development of novel small molecule inhibitors of zinc metalloenzymes that regulate proliferation and metastasis of cancer cells. Initial targets are various novel metalloproteases of the ubiquitin system p97, Csn5, Rpn11

Caltech Founders: Deshaies
CEO/President: Laura Shawver
Year Founded: 2011
Burlingame, CA 94010
United States

Clinical MicroSensors (CMS)

Life science

Nucleic Acid Detection

Caltech Founders: Fraser, Meade
Year Founded: 1995
Exit Year: 2000
Company Status: acquired by Motorola
Pasadena, CA
United States

Code On Network Coding

Software/internet

Randomized distributed network coding

Caltech Founders: Effros
Year Founded: 2011
Belmont, WA 2481
United States

Codexis

Chemistry

Use of P450 enzymes for the discovery, development, manufacture, and commercialization of industrial chemicals, pharmaceuticals, fine chemicals, and agricultural chemicals

Caltech Founders: Arnold
CEO/President: John Nicols
Year Founded: 2007
Exit Year: 2010
Company Status: IPO
Redwood City, CA 94063
United States

Coelacanth

Chemistry

Chemical intermediates for chemical libraries for Pharmaceutical applications

Caltech Founders: Grubbs
Year Founded: 1996
Exit Year: 2001
Company Status: acquired by Lexicon
Princeton, NJ
United States

Combion

Life science

Combinatorial DNA Libraries

Caltech Founders: Baldeschweiler
Year Founded: 1994
Exit Year: 1996
Company Status: acquired by Incyte
Redwood City, CA 94063
United States

Contour Energy Systems

Physical science

Carbon fluoride based primary and rechargeable batteries and electrolytes therein

Caltech Founders: Yazami
Year Founded: 2007
Azusa, CA 91702
United States

Cyrano Sciences

Chemistry

Sensor Arrays for chemical detection/identification ("electronic nose")

Caltech Founders: Lewis
CEO/President: Steven Sunshine
Year Founded: 1997
Exit Year: 2004
Company Status: acquired by Smiths Detection
Pasadena, CA 91107
United States

Darwin Molecular

Life science

T Cell Receptors

Caltech Founders: Hood
Exit Year: 1996
Company Status: acquired by Chiroscience
United States

Digitexx Data Systems

Physical science

Structural Monitoring of buildings

Caltech Founders: Iwan
CEO/President: Mark Sereci
Year Founded: 2000
Carefree, AZ 85331
United States

Direct Methanol Fuel Cell Corp. (DMFCC)

Physical science

Direct Methanol Fuel Cells

Caltech Founders: Narayanan (JPL)
CEO/President: Carl Kukkonen
Year Founded: 2002
Pasadena, CA 91107
United States

E-ViEWS Safety Systems

Physical science

Transponders for coordination of emergency/first responder systems

Caltech Founders: Bachelder (JPL)
CEO/President: Jim Davidson
Year Founded: 2003
Agoura Hills, CA 91301
United States

Earthmine

Software/internet

Camera Calibration Software for Real-time Stereo Vision Systems

Caltech Founders: Matthies (JPL)
CEO/President: Anthony Fassero
Year Founded: 2006
Berkeley, CA 94710
United States

EndActive

Life science

Wide field-of-view endoscopy

Caltech Founders: Burdick
Year Founded: 2001
Exit Year: 2005
Company Status: acquired by Karl Storz Imaging
Arcadia, CA 91066
United States

ePetri

Life science

Wide field of view microscopy

Caltech Founders: Yang
Year Founded: 2012
Pasadena, CA 91104
United States

Escape Dynamics

Physical science

A Microwave Heat-Exchange Thruster and Method of Operating the Same

Caltech Founders: Parkin
CEO/President: Richard Schaden
Year Founded: 2010
Broomfield, CO 80021
United States

Evogh

Software/internet

Virtual room video conferencing system

Caltech Founders: Newman
Year Founded: 2006
Pasadena, CA 91101
United States

Exogene

Life science

Hemoglobin Expression

Caltech Founders: Bailey (JPL)
CEO/President: N.L. Davis
Year Founded: 1989
Pasadena, CA 91106
United States

Fastsoft

Software/internet

A faster implementation of the Transport Control Protocol (TCP), a fundamental data transmission protocol of the Internet

Caltech Founders: Low
CEO/President: Ed Snyder
Year Founded: 2005
Exit Year: 2012
Company Status: Acquired by Akamai
Pasadena, CA 91105
United States

FemtoTrace

Chemistry

ultrasensitive mass spectrometry

Caltech Founders: Chutjian (JPL)
CEO/President: Ara Chutjian
Year Founded: 2002
Exit Year: 2009
La Crescenta, CA 91214
United States

Filtini

Life science

Uses of Parylene Membrane Filters for trapping circulating tumor cells

Caltech Founders: Tai
Year Founded: 2010
Los Altos, CA 94022
United States

FitMe.Com

Software/internet

Cloth simulation used for 3D wardrobe/catalog and virtual fitting rooms, for textile, apparel & accessories

Caltech Founders: Schroeder, Desbrun
CEO/President: Ram Srinivasan
Year Founded: 2000
Santa Clara, CA 95051
United States

Fluidigm

Life science

Microfluidic-based chips and instrumentation for biological research

Caltech Founders: Quake
CEO/President: Gajus Worthington
Year Founded: 1999
Exit Year: 2012
Company Status: IPO
South San Francisco, CA 94080
United States

Folda

Life science

Forming in-situ cardiac valve stent that collapses into non-convex structures

Caltech Founders: Gharib
Year Founded: 2010
Mission Viejo, CA 92692
United States

Fulcrum Microsystems

Physical science

Asynchronous digital circuits

Caltech Founders: Martin
CEO/President: Uri Cummings
Year Founded: 2001
Exit Year: 2011
Company Status: acquired by Intel
Calabasas, CA 91302
United States

GeneOhm

Life science

Nucleic acid-based diagnostics

Caltech Founders: Barton
Year Founded: 2000
Exit Year: 2006
Company Status: acquired by BD Diagnostics
United States

Genesoft

Life science

DNA-binding polyamides

Caltech Founders: Dervan
Year Founded: 1997
Company Status: acquired by Oscient
South San Francisco, CA 94080
United States

Geometrix

Software/internet

3-D rendering

Caltech Founders: Perona
Year Founded: 1999
Company Status: acquired by Alive Tech
San Jose, CA 95126
United States

Gevo

Chemistry

Developing biobased alternatives to petroleum-based products using a combination of synthetic biology and chemistry

Caltech Founders: Arnold
CEO/President: Patrick R. Gruber
Year Founded: 2005
Exit Year: 2012
Company Status: IPO
Englewood, CO 80112
United States

GlassiMetal Technology

Physical science

Rapid discharge forming/ohmic heating technique to heat a metallic glass material uniformly and rapidly

Caltech Founders: Johnson
Year Founded: 2011
Pasadena, CA 91107
United States

Helicos Biosciences

Life science

Single-molecule nucleic acid sequencing

Caltech Founders: Quake
CEO/President: Ivan Trifunovich
Year Founded: 2004
Exit Year: 2007
Company Status: IPO
Cambridge, MA 02139
United States

Helixis

Life science

Thermal Cycler for real-time PCR

Caltech Founders: Scherer
Year Founded: 2007
Exit Year: 2010
Company Status: acquired by Illumina
Carlsbad, CA
United States

High Tower Software

Software/internet

Data Monitoring Systems & Software MSAS; SEQGEN; DVIEW; Cyberspace Monitoring System

Caltech Founders: Schwuttke
CEO/President: Gordon Smith
Year Founded: 1997
Exit Year: 2008
Aliso Viejo, CA 92656
United States

Holoplex

Physical science

Holographic Storage

Caltech Founders: Psaltis
CEO/President: Fai Mok
Year Founded: 1995
Company Status: acquired by Aprilis
Pasadena, CA 91106
United States

ImagerLabs

Physical science

High-performance CMOS sensors for imaging and non-imaging apps

Caltech Founders: Wadsworth (JPL)
CEO/President: Eugene Atlas
Year Founded: 2001
Monrovia, CA 91016
United States

Immune Design Corp.

Life science

Dendritic cell-targeted vaccine delivery using lentiviral vectors

Caltech Founders: Baltimore
CEO/President: Carlos Paya
Year Founded: 2009
Seattle, WA 98104
United States

Impinj

Physical science

RFID

Caltech Founders: Mead
CEO/President: William Colleran
Year Founded: 2000
Seattle, WA 98103
United States

Insert Therapeutics

Life science

Drug delivery using Linear Cyclodextrin Polymers

Caltech Founders: Davis
Year Founded: 1998
Company Status: acquired by Calando
Pasadena, CA 91107
United States

InSilixa

Life science

High-performance CMOS biochips for microarray technology

Caltech Founders: Hassibi
Year Founded: 2010
TX?
United States

Integrated Diagnostics

Life science

Large-scale, blood-based molecular diagnostics

Caltech Founders: Heath
CEO/President: Albert A. Luderer
Year Founded: 2008
Seattle, WA 98109
United States

Integrated Micromachines

Physical science

Micromachine Technology

Caltech Founders: Tai
Year Founded: 1997
Exit Year: 2004
Company Status: acquired by Touchdown Technologies
Monrovia, CA 91016
United States

Intelligent Ion

Chemistry

Mass spectrometry

Caltech Founders: Sinha (JPL)
Year Founded: 2001
Exit Year: 2004
Company Status: acquired by OI Corporation
College Station, TX 77842
United States

Ion Optics

Physical science

silicon micro-machined infrared detectors

Caltech Founders: George (JPL)
CEO/President: Edward Johnson
Year Founded: 2001
Exit Year: 2005
Company Status: acquired by ICx
Waltham, MA 02452
United States

IONfinity

Chemistry

"Soft-ionization" technology for next-generation mass spectrometers, differential mobility spectrometers and systems dependent on ion-level sampling for industrial process control, biomedical, and environmental monitoring and possibly new detection systems for homeland security

Caltech Founders: Smith, Hartley (JPL)
CEO/President: Carl Kukkonen
Year Founded: 1998
Pasadena, CA 91106
United States

iSpheres

Physical science

Distributed object computing

Caltech Founders: Chandy
CEO/President: Deepak Gupta
Year Founded: 1999
Pleasanton, CA 94588
United States

Journal Fire

Software/internet

Managing and conducting scholarly journal clubs on the web

Caltech Founders: Delacruz
CEO/President: John Delacruz
Year Founded: 2009
Pasadena, CA 91106
United States

Kelvin Volta, Inc. (KVI)

Physical science

Battery Assessment

Caltech Founders: Yazami
Year Founded: 2010
United States

Kuros Biosurgery

Life science

Implantation technology for use with animals and humans

Caltech Founders: Hubbell
Year Founded: 2003
n/a
Switzerland

Kuros Therapeutics

Life science

Cell Ingrowth or Tissue Regeneration Matrix.

Caltech Founders: Hubbell
CEO/President: Didier Cowling
Year Founded: 2000
Exit Year: 2002
Company Status: acquired by Straumann AG
n/a
Switzerland

LeukoDx LP

Life science

Compact table-top and hand-held fluoro cytometry instruments based on microfluidics technology

Caltech Founders: Tai
CEO/President: Julien Meissonnier
Year Founded: 2009
Towson, MD 21204
United States

Lightcross

Physical science

Optical Components

Caltech Founders: Wu (JPL)
CEO/President: Chi Wu
Year Founded: 2000
Monterey Park, CA 91754
United States

Liquidmetal

Physical science

Metallic Glasses

Caltech Founders: Johnson
CEO/President: John Kang
Year Founded: 1993
Exit Year: 2002
Company Status: IPO
Rancho Santa Margarita, CA 92688
United States

Luxtera

Physical science

Construction of complex optical systems in production CMOS processes

Caltech Founders: Scherer
CEO/President: Greg Young
Year Founded: 2000
Carlsbad, CA 92011
United States

Materia

Chemistry

Olefin metathesis catalyst technology

Caltech Founders: Grubbs
CEO/President: Michael A. Giardello
Year Founded: 1994
Pasadena, CA 91107
United States

Matter

Physical science

Plasmon-assisted chemical reactions

Caltech Founders: Boyd
CEO/President: Anthony DeFries
Year Founded: 2005
Los Angeles, CA 90049
United States

Maxygen

Life science

Improved next-generation G-CSF protein for the treatment of chemotherapy-induced neutropenia (CIN) and acute radiation syndrome (ARS)

Caltech Founders: Arnold
CEO/President: James R. Sulat
Year Founded: 1998
Company Status: IPO
San Mateo, CA 94402
United States

Medical Technologies International (MTI)

Life science

Non-invasive ultrasound diagnostic products for heart disease and stroke

Caltech Founders: Selzer (JPL)
CEO/President: Gary F. Thompson
Year Founded: 2000
Palm Desert, CA 92211
United States

Melcure

Life science

Cancer diagnosis and treatment methods

Caltech Founders: Patterson
Year Founded: 2006
n/a
United States

Mindbrook

Software/internet

CMIS and RecDel S/W

Caltech Founders: Wilcox (JPL)
CEO/President: Cyril Rayan
Year Founded: 2002
Santa Clara, CA 95054
United States

Mobila

Software/internet

Knowledge-based, massive data mining and computational intensive applications/new generation of mobile device applications based on SHINE software

Caltech Founders: James (JPL)
CEO/President: AJ Abdallat
Year Founded: 2011
Thousand Oaks, CA 91360
United States

Modelogic

Physical science

On-chip manipulation of light and electricity

Caltech Founders: Scherer
Year Founded: 2005
Exit Year: 2008
United States

Myricom

Physical science

High Performance Computing (HPC) interconnect (Ethernet) technology

Caltech Founders: Seitz (JPL)
CEO/President: Nanette Boden
Year Founded: 1995
Arcadia, CA 91006
United States

Nanotechnica

Life science

lab-on-a-chip, including biosensors, microfluidics, and sample preparation

Caltech Founders: Roukes, Fraser, Tai
Year Founded: 2004
Exit Year: 2005
Pasadena, CA 91101
United States

Neurion Pharmaceuticals

Life science

Use of unnatural amino acids and codon optimization applied to ion channels and other membrane proteins, for heterologous expression in oocytes and cloned mammalian cell lines

Caltech Founders: Dougherty
Year Founded: 2002
Exit Year: 2008
Pasadena, CA 91103
United States

NeuroRecovery Technologies

Life science

Neurostimulator technology for recovery of neurological function

Caltech Founders: Burdick, Tai
Year Founded: 2011
CA
United States

Next Dimension Technologies

Chemistry

Sensors designed using nanotechnology-based materials and transducers that exhibit remarkable sensitivity and fast responses towards a broad set of chemical vapors

Caltech Founders: Lewis
CEO/President: William J. Royea
Year Founded: 2005
Pasadena, CA 91103
United States

Nextreme Thermal Solutions

Physical science

Micro-scale thermal and power management products that overcome thermal and power constraints in electronics

Caltech Founders: Fleurial (JPL)
CEO/President: John Goehrke
Year Founded: 2006
Durham, NC 27703
United States

Oak Grove Systems

Software/internet

Online workflow management

Caltech Founders: Ames (JPL)
CEO/President: Chuck Ames
Year Founded: 1999
Altadena, CA 91001
United States

OEwaves

Physical science

Microwave photonic technologies for communications, radar, and test and measurement systems

Caltech Founders: Maleki (JPL)
CEO/President: Lute Maleki
Year Founded: 1999
Pasadena, CA 91107
United States

Omnicorder Technologies

Physical science

Quantum Well Infrared Photodetector Devices for the detection of breast cancer

Caltech Founders: Gunapala (JPL)
CEO/President: Denis A. O'Connor
Year Founded: 1997
Bohemia, NY 11716
United States

Ondax

Physical science

Holographic optical filters and wavelength-stabilized laser sources

Caltech Founders: Psaltis
CEO/President: Randy Heyler
Year Founded: 2001
Monrovia, CA 91016
United States

One-Cycle Control

Physical science
Year Founded: 2004
United States

oProbe

Life science

Forward scanning imaging optical fiber probe

Caltech Founders: Yang
CEO/President: Jeff Brennan
Year Founded: 2010
Pasadena, CA 91103
United States

Oraxion

Physical science

Process control metrology systems for semiconductor manufacturers

Caltech Founders: Rosakis
CEO/President: Bang Nguyen
Year Founded: 2002
Exit Year: 2006
Company Status: assigned to Ultratech
Fremont, CA 94539
United States

Orbits Lightwave

Physical science

Fiber ring laser

Caltech Founders: Yariv
CEO/President: Yaakov Shevy
Year Founded: 2000
Pasadena, CA 91105
United States

Pacific Scanning Corp

Physical science

Elemental Analysis & Surface Imaging

Caltech Founders: Kossakovski (JPL)
CEO/President: Gary Aden
Year Founded: 1999
Company Status: acquired by Agilent
Santa Clara, CA 95054
United States

Pasadena Labs

Software/internet

Pricing/promotion optimization through sales data analysis

Caltech Founders: Camerer
CEO/President: Brad Feldman
Year Founded: 2013
Pasadena, CA 91030
United States

Pharma Genomix

Life science

Single DNA Molecule Analysis

Caltech Founders: Quake, Anderson (JPL)
CEO/President: Bruce Burrows
Year Founded: 2001
Santa Clarita, CA 91380
United States

PharmSelex

Life science

In silico prediction of the structures of G-protein coupled receptors (GPCRs) and ligands which bind those GPCRs.

Caltech Founders: Goddard
CEO/President: Carl Weissman
Year Founded: 2008
Seattle, WA 98102
United States

Phasebridge

Physical science

Optical waveguides

Caltech Founders: Logan (JPL)
Year Founded: 2000
Exit Year: 2005
Company Status: acquired by EMCORE
United States

Phononic Devices

Physical science

Thermoelectric material technology

Caltech Founders: Snyder
CEO/President: Anthony Atti
Year Founded: 2012
Durham, NC 27713
United States

Photobit

Physical science

CMOS APS Image Sensors

Caltech Founders: Fossum
Year Founded: 1996
Exit Year: 2002
Company Status: acquired by Micron
United States

Photon Etc.

Physical science

Tunable filter for astronomical telescopes for imaging whole optical bandwidths

Caltech Founders: Blais-Ouellette
CEO/President: Sebastien Blais-Ouellette
Year Founded: 2004
Montreal, n/a
Canada

PowerPhysics

Physical science

Audio amplifiers based on One-Cycle-Sound pulse width generation circuit

Caltech Founders: Smedley
Year Founded: 2001
Newport Beach, CA 92663
United States

PreDx

Life science

MRI Diagnostics

Caltech Founders: Fraser
Year Founded: 2007
Wilmette, IL 60091
United States

Prolinx

Life science

Conjugated Polyamides

Caltech Founders: Dervan
CEO/President: Gregory B. Abbott
Year Founded: 1997
Exit Year: 2003
Company Status: acquired by Cambrex Bioscience
Bothell, WA 98021
United States

Protabit

Life science

Next generation protein design software tools for high-throughput protein design and optimization

Caltech Founders: Mayo
CEO/President: Barry Olafson
Year Founded: 2009
Pasadena, CA 91101
United States

Proteolix

Life science

Proteasome protein targets

Caltech Founders: Deshaies
CEO/President: Susan Molineaux
Year Founded: 2004
Exit Year: 2009
Company Status: acquired by Onyx
South San Francisco, CA 94080
United States

Provivi

Chemistry

Heme enzyme-catalyzed cyclopropanation

Caltech Founders: Arnold
Year Founded: 2013
1701 Colorado Ave
Santa Monica, CA 90404
United States

QWIP Technologies

Physical science

Quantum Well Infrared Detectors

Caltech Founders: Gunapala (JPL)
Year Founded: 1999
Exit Year: 2006
Company Status: acquired by Cantronic
Brea, CA 92821
United States

RAINfinity

Software/internet

Reliable Array of Distributed Computer Nodes

Caltech Founders: Bruck
CEO/President: Charles Fan
Year Founded: 1998
Exit Year: 2005
Company Status: acquired by EMC
San Jose, CA 95134
United States

Replenish Pumps

Life science

Drug delivery

Caltech Founders: Tai
CEO/President: Sean Caffey
Year Founded: 2008
Pasadena, CA 91107
United States

Rockoco

Physical science

Enhancing the optical characteristics of a gemstone

Caltech Founders: Scherer, Maltezos
Year Founded: 2009
Carlsbad, CA 92009
United States

SAFCell

Physical science

Solid acid fuel cells

Caltech Founders: Haile
CEO/President: Calum Chisholm
Year Founded: 2010
Pasadena, CA 91106
United States

SeaTrec

Physical science

Phase change material thermal power generator

Caltech Founders: Chao (JPL)
Year Founded: 2013
United States

Sensors in Motion

Physical science

MEMS Gyroscope Technology; DRG Design S/W

Caltech Founders: Shcheglov (JPL)
CEO/President: David Smukowski
Year Founded: 2005
Bellevue, WA 98004
United States

Sensorware Systems

Physical science

Intelligent sensor infrastructure for real-time monitoring and resource management

Caltech Founders: Delin (JPL)
CEO/President: Kevin Delin
Year Founded: 2004
Arcadia, CA 91007
United States

Sigma Squared Decisions, Inc.

Software/internet

START software: Systematic Approach for Selection of R&D Technology Portfolios

Caltech Founders: Lincoln (JPL)
CEO/President: Steven Conner
Year Founded: 2013
Chula Vista, CA 91921
United States

Silicium Energy

Physical science

Nanomesh and nanowire technologies

Caltech Founders: Heath, Goddard
CEO/President: Akram Boukai
Year Founded: 2012
Ann Arbor, MI 48108
United States

Situs Logic

Physical science

Asynchronous VLSI technology for ultra-reliable electronic systems in safety-critical applications

Caltech Founders: Martin
Year Founded: 2011
Pasadena, CA 91106
United States

Skull Base Institute

Life science

Stereo Imaging Miniature Endoscope with a Single Chip and Conjugated Multi-bandpass Filters

Caltech Founders: Manohara (JPL)
CEO/President: Hrayr Shahinian
Year Founded: 2007
Los Angeles, CA 90048
United States

SlipChip

Life science

Valveless and pumpless microfluidic devices

Caltech Founders: Ismagilov
CEO/President: Brian Coe
Year Founded: 2013
Pasadena, CA
United States

Snapshot Spectra

Chemistry

Computer Tomography Imaging Spectrometer (CTIS)

Caltech Founders: Bearman (JPL)
CEO/President: Gregory H. Bearman
Year Founded: 2007
Pasadena, CA 91104
United States

Solarbre

Chemistry

Photoresponsive sunscreen

Caltech Founders: Stowell
Year Founded: 1997
Boulder, CO 80301
United States

Sonic Innovations

Life science

Hearing Aid Technology

Caltech Founders: Mead
Year Founded: 1996
Salt Lake City, UT 84117
United States

SpectraSensors

Physical science

Tunable diode laser analyzers/Strained layer quantum well lasers

Caltech Founders: Forouhar (JPL)
CEO/President: George Balogh
Year Founded: 1999
Houston, TX 77043
United States

Spreadsheet World

Software/internet

ICEMaker engineering software

Caltech Founders: Sercel
CEO/President: Tom Mincer
Year Founded: 2002
Encino, CA 91426
United States

Superprotonic

Physical science

Solid acid fuel cells

Caltech Founders: Haile
CEO/President: Calum Chisholm
Year Founded: 2005
Exit Year: 2009
Pasadena, CA 91105
United States

Trellis Photonic Communications

Physical science

Holographic Storage & Optical Computing

Caltech Founders: Yariv
CEO/President: Elon Littwitz
Year Founded: 1998
Exit Year: 2003
n/a Jerusalem
Israel

Ubu Communications

Physical science

Lithium niobate technology useful in stabilizing modulators used in telecommunications

Caltech Founders: Bridges
Year Founded: 2000
Company Status: acquired by New Focus
San Jose, CA 95136
United States

Ultrafast Sensors and Applications

Physical science

Photonic based sensing

Caltech Founders: Soares
Year Founded: 1994
CO
United States

Umachines

Physical science

Shear stress sensors useful for external/internal gas and liquid flow

Caltech Founders: Tai
CEO/President: Thomas R. Tsao
Year Founded: 1999
Altadena, CA 91001
United States

Universal Phase

Physical science

Energy systems and materials processing

Caltech Founders: Barmatz (JPL)
CEO/President: Neel Master
Year Founded: 2009
Santa Monica, CA 90403
United States

Vasgene

Life science

Innovative therapeutics based on new understandings in vascular biology

Caltech Founders: Anderson
Year Founded: 2000
Los Angeles, CA
United States

Veros

Software/internet

Real-Time Recurrent learning of Spatio-Temporal Patterns.

Caltech Founders: Atiya (visiting scientist in Abu-Mostafa lab)
Year Founded: 2001
United States

Verrix

Life science

Bacterial spore detection for verification of disinfection procedures

Caltech Founders: Ponce (JPL)
Year Founded: 2013
Los Angeles, CA
United States

Vestar

Life science

Liposomes, triple-helical DNA

Caltech Founders: Baldeschwieler, Dervan
Year Founded: 1985
Exit Year: 1999
Company Status: acquired by Gilead
United States

ViaChange

Software/internet

SHINE Software

Caltech Founders: James (JPL)
CEO/President: Carl Kukkonen
Year Founded: 2000
Pasadena, CA 91107
United States

Vialogy Corp.

Software/internet

SHINE Software

Caltech Founders: James (JPL)
CEO/President: Douglas C. Lane
Year Founded: 2002
Altadena, CA 91001
United States

Viaspace

Physical science
CEO/President: Carl Kukkonen
Year Founded: 1998
Pasadena, CA 91107
United States

VioSense Corporation

Physical science

3D Camera & Laser Doppler Velocimeters

Caltech Founders: Gharib
CEO/President: Darius Modarress
Year Founded: 2001
Company Status: acquired by Measurement Science Enterprise
Pasadena, CA 91106
United States

VisionRx.com

Life science

Computer Driven Optical Keratometer and Method of Evaluating the Shape of the Cornea

Caltech Founders: Baroth (JPL)
CEO/President: Jeffrey L. Stewart
Year Founded: 1995
Elmsford, NY 10523
United States

Visualyze Technologies

Physical science

Phase imaging microscopy

Caltech Founders: Yang
CEO/President: George Rakuljic
Year Founded: 2010
Santa Monica, CA 90403
United States

Volcano Therapeutics

Life science

Atherosclerotic plaque detection and/or treatment

Caltech Founders: Bearman (JPL)
Year Founded: 2001
Exit Year: 2006
Company Status: IPO
Houston, TX 77056
United States

VRVS Global

Software/internet

VRVS Conferencing System

Caltech Founders: Newman (JPL)
CEO/President: Aidan Foley
Year Founded: 2002
Pasadena, CA 91106
United States

Wavestream Wireless Technologies

Physical science

High Frequency Power Amplifiers

Caltech Founders: Rutledge
Year Founded: 2000
Exit Year: 2011
Company Status: acquired by Gilat
San Dimas, CA 91773
United States

Xen Golf

Physical science

Golf Putter

Caltech Founders: Wolf
CEO/President: Jeff Abel
Year Founded: 1999
Evanston, IL 82931
United States

Xencor

Life science

Automated Computational Design of Proteins

Caltech Founders: Mayo
CEO/President: Bassil I. Dahiyat
Year Founded: 1997
Monrovia, CA 91016
United States

Xponent

Physical science

Resonant Optical Wave Power Control Devices and Methods

Caltech Founders: Vahala
CEO/President: Peter C. Sercel
Year Founded: 2000
Company Status: acquired by Hoya Corp
Monrovia, CA 91016
United States